The outstanding success of Radiesse® recently added another milestone to its remarkable history. What does Radiesse® have in common with Rio de Janeiro or hummingbirds? Get to know the newest chapter of this filler’s unique success story.

Would you love to feel better in your skin? Of course you would. We all want to look younger and fresher. 50 % of men and women in Europe are concerned about ageing. Studies show that women in particular fear losing their youth, confidence and attractiveness with age. But what happens to the skin as we get older? With ageing, the skin loses moisture, tension and elasticity. The former clear contours of the face disappear. With Radiesse® you can get back a youthful appearance. The aesthetic wrinkle and volume treatment with this unique dermal filler gives your skin a lifting and contouring effect.



Healthy young skin contains collagen that gives it volume, elasticity and strength. As part of the ageing process, your own natural collagen gradually breaks down. This loss of elasticity and volume results in wrinkles, facial lines and skin laxity, reducing the youthful appearance of your face.


Radiesse® is an injectable dermal filler that temporarily adds volume to help smooth moderate to severe facial wrinkles and gives an immediate lifting and firming effect on the skin. Once injected, Radiesse® directly provides volume and lift needed to diminish the signs of ageing because of the calcium-based microspheres and gel that comprise the product. Both the gel and the microspheres are completely broken down by the body over time.


In addition to an immediate filling effect, the high-quality ingredients of Radiesse® stimulate the skin’s natural collagen synthesis. Thanks to the collagen-inducing effect of Radiesse®, the skin regains its youthful tightness and elasticity – your natural beauty blooms again.


The line extension product, Radiesse® Lidocaine, has been approved by the FDA (the American regulatory authority) and bears the CE mark, which is the European Union’s standard for product safety. The addition of integral lidocaine reliably enhances patient comfort, and combines the excellent lifting and contouring effects of the proven dermal filler Radiesse® with significant pain reduction.*

* Schachter Science Brief: Pain Control using the Injectable Dermal Filler Radiesse ®(+) for the correction of Nasolabial folds. Daniel Schachter, Vince Bertucci, Nowell Solish. POSTER PRESENTATION at 13th Anti-Aging Medicine World Congress (2015), Monaco, Monte Carlo.


Radiesse® is composed of small calcium hydroxylapatite (CaHA) microspheres suspended in a soft gel matrix. Radiesse® is gently injected by your physician into the skin, usually in small amounts with a very fine needle. For additional treatment comfort, the doctor may apply a local anaesthetic to treated areas. This injection provides an immediate and visible effect. Additionally, Radiesse® stimulates your skin’s own regeneration abilities – new collagen is produced over the following weeks and months, making your skin stronger and more elastic. Radiesse® treatment results are long-lasting, but not permanent. Many patients come back to repeat treatments because they are very happy with them. 90 % of men and women are satisfied with the treatment results of Radiesse®.1

1 Moers-Carpi M, et al. Dermatol Surg. 2007 Dec; 33 Suppl 2: S144–51

Mode of Action

Once injected, Radiesse® provides immediate volume and correction but also continues to work by stimulating the skin to produce its own natural collagen. Over time, the gel is absorbed and the body metabolises the CaHA microspheres, leaving behind only the skin’s natural collagen.


spa-sun-screen Once injected, Radiesse® shows an immediate one-to-one correction and lifting effect. It can instantly soften your smile lines, replace lost volume in your cheeks, or contour your jawline. One study* showed that Radiesse® Lidocaine achieves the same treatment outcome as Radiesse® and results in significant pain reduction during and throughout the first hour after treatment.

* Schachter Science Brief: Pain Control using the Injectable Dermal Filler Radiesse ®(+) for the correction of Nasolabial folds. Daniel Schachter, Vince Bertucci, Nowell Solish. POSTER PRESENTATION at 13th Anti-Aging Medicine World Congress (2015), Monaco, Monte Carlo.


spa-sun-screen Over the following weeks, Radiesse® microspheres stimulate the skin to produce new collagen for a soft, natural look.


spa-sun-screen Newly formed collagen surrounds the microspheres. The microspheres are eventually metabolised by the body’s normal processes.


spa-sun-screen The new collagen provides a long-term effect that may last for a year or more in many patients.*

* Individual results are dependent on age, skin type, lifestyle, metabolism and, of course, the area treated.

What to Expect

The ideal way to achieve wrinkle reduction is by replenishing lost volume. Unfortunately, treating individual wrinkles is often not enough to restore a youthful and fresh appearance. In order to counter the effects of gravity and regain a younger shape, the face needs real lifting. With Radiesse®, you welcome back your skin’s natural collagen to smooth out sagging effects.

The unique formulation of Radiesse® stimulates the production of new collagen, which results in increased volume that may last a year or more in many patients*. Thanks to this method of wrinkle correction, Radiesse® is more and more becoming the favourite injectable filler of many patients and medical professionals.

Our Radiesse® model has tried it herself! See her story:

Like other treatments with dermal fillers, Belotero® filler injections will take about 30 minutes to complete. Wrinkle filling, facial contouring and rehydration treatments are virtually painless. Some people may experience the treatment as a mild discomfort. Therefore, nearly the complete Belotero® range is available with lidocaine to enhance your treatment comfort.

The Belotero® products are hypoallergenic fillers and usually do not require a skin test prior to injection**. The aesthetic results are immediate and you will be able to continue your daily activities as soon as your appointment is over.

“Being a model means doing something that I really love. I especially like the variety in my job. But modelling is also a full-time occupation that requires constant attention. My daily life with all the travelling from one appointment or casting to another often made me look stressed and tired. I thought that I looked older than I felt. Due to the nature of my job, I am confronted every day with people who all want to look the best they can. Modelling is extremely competitive.

So I asked myself: How can I achieve an overall fresher look? I had tried every kind of cream and lotion before without a noticeable improvement. Because I wanted to keep my natural look, surgical lifting was never an option for me. I wanted a radiant appearance, a slight lifting of my whole face, a discreet balancing of wrinkles – but without losing the typical characteristics of my face. My dermatologist recommended Radiesse® to me. Radiesse® strikes a balance between cream and plastic surgery. It is used to stimulate the formation of collagen, to replace lost volume and tighten facial contours. He told me that especially my nasolabial folds could be easily reduced with Radiesse®. Being a model, I am very thin and therefore I also had hollow cheeks, which I wanted to compensate. After a detailed consultation, my dermatologist started the treatment with Radiesse®.

The treatment took just half an hour and the result was amazing! I looked in the mirror and felt fresher and healthier than ever and just comfortable in my own skin. And I kept my natural unique look – just even better.”

What makes Radiesse® special

With just one syringe, many patients obtain an immediate and long-lasting youthful appearance. A Radiesse® treatment is simple, quick, comfortable and convenient and provides immediately visible results that last.

  • Immediate correction of moderate to severe wrinkles
  • Immediate lifting and contouring effects
  • Stimulates the production of the skin’s natural collagen
  • Long-term improvement of skin quality
  • Feels soft and looks natural
  • Provides results that last a year or more in many patients*
  • Allows for an easy and convenient treatment
  • Also available with lidocaine for enhanced treatment comfort
  • Radiesse® Lidocaine offers significant pain reduction and can be used for the same aesthetic indications as Radiesse®



Safe and Effective Treatment

Radiesse® offers you a safe and convenient way to regain the youthful contours of your face. A Radiesse® treatment can be performed during a single visit at your practitioners’ office and the results are immediately visible. Moreover, Radiesse® has a very favourable safety profile:

  • Radiesse® consists of time-tested and biocompatible materials with over 20 years of use in medicine.
  • There is no need for an allergy test prior to Radiesse® injections since the microspheres are comprised of a substance naturally found in the body.
  • Through years of clinical studies, Radiesse® has been proven to be safe and effective and has demonstrated excellent tolerability.
  • More than 6 million packs of Radiesse® have been used for aesthetic treatments worldwide.
  • The lifting und contouring effect of Radiesse® lasts up to one year or more without repeat treatments.
  • Radiesse® can be safely combined with some other fillers, such as hyaluronic acid. Do you want to have your lips contoured or mimic wrinkles treated as well to complement your regained youthful appearance? Please ask your practitioner for advice and further information.


Important Radiesse® treatment considerations

Radiesse® is approved by the FDA for subdermal implantation to correct moderate to severe facial wrinkles and folds, such as nasolabial folds. After injection, patients may experience symptoms such as redness, bruising or swelling. Most side effects of treatment disappear within a few days. Rarer side effects may include more persistent swelling, unevenness or firmness in the area injected. As with any injection, there may be a risk of infection. However, side effects occurring after Radiesse® treatment are generally mild and of short duration. Please discuss any concerns you have with your practitioner.

Why choose Radiesse®?

  • Radiesse® is the only injectable dermal filler that immediately replenishes lost volume, gives the lift you need to produce an overall smoother, more youthful appearance, and stimulates the skin’s natural collagen to grow. This process continues for several months, extending the positive initial effect.
  • Treatment with Radiesse® is quick. There is little to no down-time involved in a Radiesse® treatment. In fact, most patients return to their daily activities right after their visit.
  • Radiesse® can be combined with several other treatments.
  • With a Radiesse® treatment you can defy the signs of ageing very effectively in a minimally invasive procedure – without surgery.
  • The natural results you can achieve with Radiesse® are clinically proven to last a year or more in many patients.*
  • Radiesse® has been very effectively applied in many patients and has a very favourable safety profile.


* Individual results are dependent on age, skin type, lifestyle, metabolism and, of course, the area treated.

Treatment Options

Radiesse® can be used effectively for moderate to deep wrinkle reduction, lifting and contouring. There are plenty of different options and also ways to combine Radiesse® with other treatments. The line extension product, Radiesse® Lidocaine, can be utilized to enhance treatment comfort. Radiesse® Lidocaine can be used for the same aesthetic indications as Radiesse®. Please ask your treating physician about which particular regions of your face are suitable for a Radiesse® treatment and how you can achieve the ideal satisfactory result for you.

  • Effective wrinkle filling

    spa-sun-screen With age, facial features begin to sag, the face loses its contours and wrinkles develop. Radiesse® offers safe, effective and easy reduction of moderate to deep lines.

    With advancing age, gradual loss of collagen and elastin fibers in the dermis contribute to wrinkle formation. Marionette lines and smile lines also known as nasolabial folds, manifest as facial volume begins to deplete. The face begins to look tired, angry or sad even when we are in a fantastic mood. Replenishing lost volume and providing lift are two keys to diminishing the appearance of facial wrinkles, lines and folds. A non-invasive and long-lasting treatment of these typical signs of ageing can be performed with a dermal filler such as Radiesse®.

    Now FDA-Approved: Radiesse® for volume correction in the hands

    spa-sun-screen Hands are often the first place to show the signs of ageing. A loss of volume makes veins and tendons more visible. Radiesse® received approval by the Food and Drug Administration (FDA) for volume replenishment in hands giving hands a natural-looking appearance. The FDA is responsible for protecting the public health by assuring the safety, efficacy and security of among other things medical devices, such as Radiesse®, and is valid for the US market and countries that follow the FDA approval. Please ask your practitioner for further information.

    Our hands are an important part of the way we communicate and present ourselves. Beautiful hands give us the confidence to express ourselves in any situation. However, hands are often the first place to show the signs of ageing and can become a frequently underrated problem area not only in thin and athletic women: The skin on our hands is thinner than that on our face and is constantly exposed to the sun and its photo-damaging effects, making it more sensitive to the ageing process. Over time, the fatty tissue beneath the skin on our hands becomes thinner. Veins and tendons become more visible and the skin loses volume. With growing options for facial aesthetics, the hands can seem noticeably older than the rest of the body.

  • Aesthetic options for male skin


    More and more men are interested in aesthetic treatments. Looking good is a factor for success. Radiesse® offers attractive treatment options for male skin.

    Regardless of age, the skin of a man is thicker than the skin of a woman and has more collagen. Men therefore experience less wrinkling and tend to age slower than women. Male skin ageing is a gradual, ongoing process that is strongly affected by environmental factors. Sun exposure, bad nutrition habits, and occupational or personal stress take their toll on male skin. Especially the main structural protein of the dermis, collagen, is increasingly broken down and lost at a rate of about 1 % per year. The consequences: firm skin loses its elasticity, and wrinkles and folds begin to form. Fortunately, today signs of ageing no longer have to be accepted as inevitable. Men can address their cosmetic concerns by choosing a high-end treatment strategy, which leads to natural-looking improvements without compromising masculinity.

    Radiesse® sharpens your profile

    Today, cosmetic procedures are commonplace for men, and like women they are taking advantage of the many benefits these treatments have to offer. Dermal fillers that support the regeneration of dermal structures are particularly effective in the treatment of male ageing skin. With its innovative microsphere technology, the next generation filler Radiesse® counteracts male skin ageing with its unique mode of action. The innovative and safe gel formula of Radiesse® contains calcium microspheres (CaHA) which stimulate the body to produce collagen, resulting in immediate and long-lasting volume augmentation. The result: The skin regains its youthful tightness and elasticity, contours become firmer.

    Radiesse® can be used effectively for moderate to deep wrinkle reduction, lifting and contouring. In these treatment areas, Radiesse® can offer you convincing results:

    • Cheeks
    • Nasolabial folds
    • Marionette lines
    • Jawline/Mandibular angle
    • Chin